Clean It Time

I have installed malwarebytes anti-malware(free), super antispyware(free), MSE and Comodo Firewall(free) in my computer. Will my computer work fine or is too much overloader? Any other good combination of these kinds of software?

Also I want to install Glary utilities for cleaning up registry, defrag and those kind of things. Will it interfere with the MSE, comodo, etc that I have?

Answers will be gladly appreciated.

I use Avast, MBAM, and super, all live, and work fine, and I use ccleaner to clean, what you have is ok, will work just fine.